Macrophage deactivation. Altered kinetic properties of superoxide-producing enzyme after exposure to tumor cell-conditioned medium.
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چکیده
منابع مشابه
Macrophage deactivation. Altered kinetic properties of superoxide- producing enzyme after exposure to tumor cell-conditioned medium
Incubation of activated mouse peritoneal macrophages with tumor cell-conditioned medium (TCM) results in their deactivation, as measured by ability to release reactive oxygen intermediates and kill protozoal pathogens. The mechanism of suppression by macrophage deactivation factor (MDF) was studied. Inhibition of H2O2 release could not be overcome by increasing the concentration of phorbol dies...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1986
ISSN: 0022-1007,1540-9538
DOI: 10.1084/jem.164.4.1319